## Database ID URL or Descriptions # ALTERNATIVE PRODUCTS FOXP2_HUMAN Event=Alternative splicing; Named isoforms=9; Name=1; Synonyms=I; IsoId=O15409-1; Sequence=Displayed; Name=2; Synonyms=II; IsoId=O15409-3; Sequence=Not described; Name=3; Synonyms=III, IV; IsoId=O15409-2; Sequence=VSP_001558; Name=4; IsoId=O15409-4; Sequence=VSP_011532; Name=5; IsoId=O15409-5; Sequence=VSP_011532, VSP_011535, VSP_011536; Name=6; Synonyms=FOXP2-S; IsoId=O15409-6; Sequence=VSP_011538, VSP_011539; Name=7; IsoId=O15409-7; Sequence=VSP_011537; Name=8; IsoId=O15409-8; Sequence=VSP_011533, VSP_011534; Note=No experimental confirmation available.; Name=9; IsoId=O15409-9; Sequence=VSP_043464; Note=No experimental confirmation available.; # AltName FOXP2_HUMAN CAG repeat protein 44 # AltName FOXP2_HUMAN Trinucleotide repeat-containing gene 10 protein # BioGrid 125073 28 # CCDS CCDS43635 -. [O15409-4] # CCDS CCDS55154 -. [O15409-9] # CCDS CCDS5760 -. [O15409-1] # CCDS CCDS5761 -. [O15409-6] # ChiTaRS FOXP2 human # DEVELOPMENTAL STAGE Expressed in the brain at 15 and 22 weeks of gestation, with a pattern of strong cortical, basal ganglia, thalamic and cerebellar expression. Highly expressed in the head and tail of nucleus caudatus and putamen. Restricted expression within the globus pallidus, with high levels in the pars interna, which provides the principal source of output from the basal ganglia to the nucleus centrum medianum thalami (CM) and the major motor relay nuclei of the thalamus. In the thalamus, present in the CM and nucleus medialis dorsalis thalami. Lower levels are observed in the nuclei anterior thalami, dorsal and ventral, and the nucleus parafascicularis thalami. Expressed in the ventrobasal complex comprising the nucleus ventralis posterior lateralis/medialis. The ventral tier of the thalamus exhibits strong expression, including nuclei ventralis anterior, lateralis and posterior lateralis pars oralis. Also expressed in the nucleus subthalamicus bilaterally and in the nucleus ruber. {ECO:0000269|PubMed 15056695}. # DISEASE FOXP2_HUMAN Note=A chromosomal aberration involving FOXP2 is a cause of severe speech and language impairment. Translocation t(5;7)(q22;q31.2). # DISEASE FOXP2_HUMAN Speech-language disorder 1 (SPCH1) [MIM 602081] A disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech. Affected individuals have severe impairment in the selection and sequencing of fine orofacial movements which are necessary for articulation, and deficits in several facets of grammatical skills and language processing, such as the ability to break up words into their constituent phonemes. {ECO 0000269|PubMed 11586359}. Note=The disease is caused by mutations affecting the gene represented in this entry. # DOMAIN FOXP2_HUMAN The leucine-zipper is required for dimerization and transcriptional repression. {ECO 0000250}. # Ensembl ENST00000350908 ENSP00000265436; ENSG00000128573. [O15409-1] # Ensembl ENST00000360232 ENSP00000353367; ENSG00000128573. [O15409-6] # Ensembl ENST00000378237 ENSP00000367482; ENSG00000128573. [O15409-7] # Ensembl ENST00000393489 ENSP00000377129; ENSG00000128573. [O15409-2] # Ensembl ENST00000393494 ENSP00000377132; ENSG00000128573. [O15409-1] # Ensembl ENST00000403559 ENSP00000385069; ENSG00000128573. [O15409-9] # Ensembl ENST00000408937 ENSP00000386200; ENSG00000128573. [O15409-4] # Ensembl ENST00000412402 ENSP00000405470; ENSG00000128573. [O15409-8] # Ensembl ENST00000441290 ENSP00000416825; ENSG00000128573. [O15409-8] # Ensembl ENST00000635109 ENSP00000489457; ENSG00000128573. [O15409-8] # ExpressionAtlas O15409 baseline and differential # FUNCTION FOXP2_HUMAN Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. # GO_component GO:0005634 nucleus; IBA:GO_Central. # GO_function GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl. # GO_function GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding; IBA:GO_Central. # GO_function GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; IEA:Ensembl. # GO_function GO:0003677 DNA binding; IDA:UniProtKB. # GO_function GO:0003700 transcription factor activity, sequence-specific DNA binding; IDA:BHF-UCL. # GO_function GO:0042803 protein homodimerization activity; IDA:UniProtKB. # GO_function GO:0043565 sequence-specific DNA binding; IDA:BHF-UCL. # GO_function GO:0046872 metal ion binding; IEA:UniProtKB-KW. # GO_process GO:0002053 positive regulation of mesenchymal cell proliferation; IEA:Ensembl. # GO_process GO:0006351 transcription, DNA-templated; IEA:UniProtKB-KW. # GO_process GO:0007519 skeletal muscle tissue development; IEA:Ensembl. # GO_process GO:0009791 post-embryonic development; IEA:Ensembl. # GO_process GO:0021549 cerebellum development; IEA:Ensembl. # GO_process GO:0021757 caudate nucleus development; IMP:UniProtKB. # GO_process GO:0021758 putamen development; IMP:UniProtKB. # GO_process GO:0021987 cerebral cortex development; IEP:BHF-UCL. # GO_process GO:0040007 growth; IEA:Ensembl. # GO_process GO:0042297 vocal learning; IEA:Ensembl. # GO_process GO:0043010 camera-type eye development; IEA:Ensembl. # GO_process GO:0045892 negative regulation of transcription, DNA-templated; IDA:BHF-UCL. # GO_process GO:0048286 lung alveolus development; IEA:Ensembl. # GO_process GO:0048745 smooth muscle tissue development; IEA:Ensembl. # GO_process GO:0060013 righting reflex; IEA:Ensembl. # GO_process GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis; IEA:Ensembl. # GOslim_component GO:0005634 nucleus # GOslim_function GO:0001071 nucleic acid binding transcription factor activity # GOslim_function GO:0003674 molecular_function # GOslim_function GO:0003677 DNA binding # GOslim_function GO:0043167 ion binding # GOslim_process GO:0008150 biological_process # GOslim_process GO:0009058 biosynthetic process # GOslim_process GO:0034641 cellular nitrogen compound metabolic process # GOslim_process GO:0040007 growth # GOslim_process GO:0048856 anatomical structure development # GOslim_process GO:0050877 neurological system process # Gene3D 1.10.10.10 -; 1. # Genevisible O15409 HS # HGNC HGNC:13875 FOXP2 # INTERACTION FOXP2_HUMAN Q08117 AES; NbExp=3; IntAct=EBI-983612, EBI-717810; P24863 CCNC; NbExp=3; IntAct=EBI-983612, EBI-395261; Q13363-2 CTBP1; NbExp=5; IntAct=EBI-983612, EBI-10171858; P56545 CTBP2; NbExp=3; IntAct=EBI-983612, EBI-741533; Q86V42 FAM124A; NbExp=3; IntAct=EBI-983612, EBI-744506; Q13526 PIN1; NbExp=5; IntAct=EBI-983612, EBI-714158; O00560 SDCBP; NbExp=3; IntAct=EBI-983612, EBI-727004; Q96A04 TSACC; NbExp=5; IntAct=EBI-983612, EBI-740411; # IntAct O15409 15 # InterPro IPR001766 Fork_head_dom # InterPro IPR011991 WHTH_DNA-bd_dom # InterPro IPR030456 TF_fork_head_CS_2 # InterPro IPR032354 FOXP-CC # KEGG_Brite ko03000 Transcription factors # KEGG_Disease H00902 [Congenital disorder] Speech-language disorder 1 (SPCH1) # MIM 602081 phenotype # MIM 605317 gene # Organism FOXP2_HUMAN Homo sapiens (Human) # Orphanet 209908 Childhood apraxia of speech # Orphanet 251061 7q31 microdeletion syndrome # PDB 2A07 X-ray; 1.90 A; F/G/H/I/J/K=502-594 # PDB 2AS5 X-ray; 2.70 A; F/G=502-594 # PRINTS PR00053 FORKHEAD # PROSITE PS00028 ZINC_FINGER_C2H2_1 # PROSITE PS00658 FORK_HEAD_2 # PROSITE PS50039 FORK_HEAD_3 # Pfam PF00250 Forkhead # Pfam PF16159 FOXP-CC # Proteomes UP000005640 Chromosome 7 # RecName FOXP2_HUMAN Forkhead box protein P2 # RefSeq NP_001166237 NM_001172766.2 # RefSeq NP_001166238 NM_001172767.2 # RefSeq NP_055306 NM_014491.3. [O15409-1] # RefSeq NP_683696 NM_148898.3. [O15409-4] # RefSeq NP_683697 NM_148899.3. [O15409-6] # RefSeq NP_683698 NM_148900.3. [O15409-9] # RefSeq XP_016868290 XM_017012801.1. [O15409-4] # SIMILARITY Contains 1 C2H2-type zinc finger. {ECO 0000305}. # SIMILARITY Contains 1 fork-head DNA-binding domain. {ECO:0000255|PROSITE-ProRule PRU00089}. # SMART SM00339 FH # SUBCELLULAR LOCATION FOXP2_HUMAN Nucleus {ECO 0000305}. # SUBUNIT FOXP2_HUMAN Forms homodimers and heterodimers with FOXP1 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1 (By similarity). Interacts with FOXP1 (PubMed 26647308). {ECO 0000250|UniProtKB P58463, ECO 0000269|PubMed 26647308}. # SUPFAM SSF46785 SSF46785 # TISSUE SPECIFICITY Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. {ECO:0000269|PubMed 12189486}. # UCSC uc003vgx human. [O15409-1] # WEB RESOURCE FOXP2_HUMAN Name=Protein Spotlight; Note=Talking heads - Issue 51 of October 2004; URL="http //web.expasy.org/spotlight/back_issues/051"; # WEB RESOURCE FOXP2_HUMAN Name=Wikipedia; Note=FOXP2 entry; URL="https //en.wikipedia.org/wiki/FOXP2"; # eggNOG COG5025 LUCA # eggNOG KOG4385 Eukaryota BLAST swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/kblast/swissprot:FOXP2_HUMAN BioCyc ZFISH:ENSG00000128573-MONOMER http://biocyc.org/getid?id=ZFISH:ENSG00000128573-MONOMER COXPRESdb 93986 http://coxpresdb.jp/data/gene/93986.shtml DIP DIP-29004N http://dip.doe-mbi.ucla.edu/dip/Browse.cgi?ID=DIP-29004N DOI 10.1007/s00439-002-0768-5 http://dx.doi.org/10.1007/s00439-002-0768-5 DOI 10.1007/s004390050476 http://dx.doi.org/10.1007/s004390050476 DOI 10.1038/35097076 http://dx.doi.org/10.1038/35097076 DOI 10.1038/nature01025 http://dx.doi.org/10.1038/nature01025 DOI 10.1038/nature01782 http://dx.doi.org/10.1038/nature01782 DOI 10.1038/ng1285 http://dx.doi.org/10.1038/ng1285 DOI 10.1093/hmg/ddv495 http://dx.doi.org/10.1093/hmg/ddv495 DOI 10.1101/gr.2596504 http://dx.doi.org/10.1101/gr.2596504 DOI 10.1126/science.1083423 http://dx.doi.org/10.1126/science.1083423 DOI 10.1523/JNEUROSCI.5589-03.2004 http://dx.doi.org/10.1523/JNEUROSCI.5589-03.2004 EMBL AC003992 http://www.ebi.ac.uk/ena/data/view/AC003992 EMBL AC020606 http://www.ebi.ac.uk/ena/data/view/AC020606 EMBL AC073626 http://www.ebi.ac.uk/ena/data/view/AC073626 EMBL AC074000 http://www.ebi.ac.uk/ena/data/view/AC074000 EMBL AC092148 http://www.ebi.ac.uk/ena/data/view/AC092148 EMBL AC092606 http://www.ebi.ac.uk/ena/data/view/AC092606 EMBL AF337817 http://www.ebi.ac.uk/ena/data/view/AF337817 EMBL AF467252 http://www.ebi.ac.uk/ena/data/view/AF467252 EMBL AF467253 http://www.ebi.ac.uk/ena/data/view/AF467253 EMBL AF467254 http://www.ebi.ac.uk/ena/data/view/AF467254 EMBL AF467255 http://www.ebi.ac.uk/ena/data/view/AF467255 EMBL AF467256 http://www.ebi.ac.uk/ena/data/view/AF467256 EMBL AF467257 http://www.ebi.ac.uk/ena/data/view/AF467257 EMBL AF493430 http://www.ebi.ac.uk/ena/data/view/AF493430 EMBL AF515031 http://www.ebi.ac.uk/ena/data/view/AF515031 EMBL AF515032 http://www.ebi.ac.uk/ena/data/view/AF515032 EMBL AF515033 http://www.ebi.ac.uk/ena/data/view/AF515033 EMBL AF515034 http://www.ebi.ac.uk/ena/data/view/AF515034 EMBL AF515035 http://www.ebi.ac.uk/ena/data/view/AF515035 EMBL AF515036 http://www.ebi.ac.uk/ena/data/view/AF515036 EMBL AF515037 http://www.ebi.ac.uk/ena/data/view/AF515037 EMBL AF515038 http://www.ebi.ac.uk/ena/data/view/AF515038 EMBL AF515039 http://www.ebi.ac.uk/ena/data/view/AF515039 EMBL AF515040 http://www.ebi.ac.uk/ena/data/view/AF515040 EMBL AF515041 http://www.ebi.ac.uk/ena/data/view/AF515041 EMBL AF515042 http://www.ebi.ac.uk/ena/data/view/AF515042 EMBL AF515043 http://www.ebi.ac.uk/ena/data/view/AF515043 EMBL AF515044 http://www.ebi.ac.uk/ena/data/view/AF515044 EMBL AF515045 http://www.ebi.ac.uk/ena/data/view/AF515045 EMBL AF515046 http://www.ebi.ac.uk/ena/data/view/AF515046 EMBL AF515047 http://www.ebi.ac.uk/ena/data/view/AF515047 EMBL AF515048 http://www.ebi.ac.uk/ena/data/view/AF515048 EMBL AF515049 http://www.ebi.ac.uk/ena/data/view/AF515049 EMBL AF515050 http://www.ebi.ac.uk/ena/data/view/AF515050 EMBL AK131266 http://www.ebi.ac.uk/ena/data/view/AK131266 EMBL AK296957 http://www.ebi.ac.uk/ena/data/view/AK296957 EMBL AY144615 http://www.ebi.ac.uk/ena/data/view/AY144615 EMBL BC126104 http://www.ebi.ac.uk/ena/data/view/BC126104 EMBL BC143866 http://www.ebi.ac.uk/ena/data/view/BC143866 EMBL CH236947 http://www.ebi.ac.uk/ena/data/view/CH236947 EMBL CH236947 http://www.ebi.ac.uk/ena/data/view/CH236947 EMBL CH471070 http://www.ebi.ac.uk/ena/data/view/CH471070 EMBL CH471070 http://www.ebi.ac.uk/ena/data/view/CH471070 EMBL U80741 http://www.ebi.ac.uk/ena/data/view/U80741 Ensembl ENST00000350908 http://www.ensembl.org/id/ENST00000350908 Ensembl ENST00000360232 http://www.ensembl.org/id/ENST00000360232 Ensembl ENST00000378237 http://www.ensembl.org/id/ENST00000378237 Ensembl ENST00000393489 http://www.ensembl.org/id/ENST00000393489 Ensembl ENST00000393494 http://www.ensembl.org/id/ENST00000393494 Ensembl ENST00000403559 http://www.ensembl.org/id/ENST00000403559 Ensembl ENST00000408937 http://www.ensembl.org/id/ENST00000408937 Ensembl ENST00000412402 http://www.ensembl.org/id/ENST00000412402 Ensembl ENST00000441290 http://www.ensembl.org/id/ENST00000441290 Ensembl ENST00000635109 http://www.ensembl.org/id/ENST00000635109 G-Links FOXP2_HUMAN http://link.g-language.org/FOXP2_HUMAN/format=tsv GO_component GO:0005634 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634 GO_function GO:0000978 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000978 GO_function GO:0000981 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000981 GO_function GO:0001078 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001078 GO_function GO:0003677 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677 GO_function GO:0003700 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003700 GO_function GO:0042803 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042803 GO_function GO:0043565 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043565 GO_function GO:0046872 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046872 GO_process GO:0002053 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002053 GO_process GO:0006351 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006351 GO_process GO:0007519 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007519 GO_process GO:0009791 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009791 GO_process GO:0021549 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021549 GO_process GO:0021757 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021757 GO_process GO:0021758 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021758 GO_process GO:0021987 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021987 GO_process GO:0040007 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0040007 GO_process GO:0042297 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042297 GO_process GO:0043010 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043010 GO_process GO:0045892 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0045892 GO_process GO:0048286 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048286 GO_process GO:0048745 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048745 GO_process GO:0060013 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060013 GO_process GO:0060501 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060501 GOslim_component GO:0005634 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634 GOslim_function GO:0001071 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001071 GOslim_function GO:0003674 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003674 GOslim_function GO:0003677 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677 GOslim_function GO:0043167 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043167 GOslim_process GO:0008150 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008150 GOslim_process GO:0009058 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009058 GOslim_process GO:0034641 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034641 GOslim_process GO:0040007 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0040007 GOslim_process GO:0048856 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048856 GOslim_process GO:0050877 http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050877 Gene3D 1.10.10.10 http://www.cathdb.info/version/latest/superfamily/1.10.10.10 GeneCards FOXP2 http://www.genecards.org/cgi-bin/carddisp.pl?gc_id=FOXP2 GeneID 93986 http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93986 GeneTree ENSGT00800000124014 http://asia.ensembl.org/Multi/GeneTree/Image?gt=ENSGT00800000124014 HGNC HGNC:13875 http://www.genenames.org/data/hgnc_data.php?hgnc_id=HGNC:13875 HOGENOM HOG000092089 http://pbil.univ-lyon1.fr/cgi-bin/view-tree.pl?query=HOG000092089&db=HOGENOM6 HOVERGEN HBG051657 http://pbil.univ-lyon1.fr/cgi-bin/acnuc-ac2tree?query=HBG051657&db=HOVERGEN HPA CAB011488 http://www.proteinatlas.org/tissue_profile.php?antibody_id=CAB011488 HPA HPA000382 http://www.proteinatlas.org/tissue_profile.php?antibody_id=HPA000382 HPA HPA000383 http://www.proteinatlas.org/tissue_profile.php?antibody_id=HPA000383 InParanoid O15409 http://inparanoid.sbc.su.se/cgi-bin/gene_search.cgi?id=O15409 IntAct O15409 http://www.ebi.ac.uk/intact/pages/interactions/interactions.xhtml?query=O15409* InterPro IPR001766 http://www.ebi.ac.uk/interpro/entry/IPR001766 InterPro IPR011991 http://www.ebi.ac.uk/interpro/entry/IPR011991 InterPro IPR030456 http://www.ebi.ac.uk/interpro/entry/IPR030456 InterPro IPR032354 http://www.ebi.ac.uk/interpro/entry/IPR032354 Jabion 93986 http://www.bioportal.jp/genome/cgi-bin/gene_homolog.cgi?org=hs&id=93986 KEGG_Brite ko03000 http://www.genome.jp/dbget-bin/www_bget?ko03000 KEGG_Disease H00902 http://www.genome.jp/dbget-bin/www_bget?H00902 KEGG_Gene hsa:93986 http://www.genome.jp/dbget-bin/www_bget?hsa:93986 KEGG_Orthology KO:K09409 http://www.genome.jp/dbget-bin/www_bget?KO:K09409 MIM 602081 http://www.ncbi.nlm.nih.gov/omim/602081 MIM 605317 http://www.ncbi.nlm.nih.gov/omim/605317 OMA PETKLCV http://omabrowser.org/cgi-bin/gateway.pl?f=DisplayGroup&p1=PETKLCV Orphanet 209908 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=209908 Orphanet 251061 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=251061 PDB 2A07 http://www.ebi.ac.uk/pdbe-srv/view/entry/2A07 PDB 2AS5 http://www.ebi.ac.uk/pdbe-srv/view/entry/2AS5 PDBsum 2A07 http://www.ebi.ac.uk/pdbsum/2A07 PDBsum 2AS5 http://www.ebi.ac.uk/pdbsum/2AS5 PRINTS PR00053 http://umber.sbs.man.ac.uk/cgi-bin/dbbrowser/sprint/searchprintss.cgi?display_opts=Prints&category=None&queryform=false&prints_accn=PR00053 PROSITE PS00028 http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00028 PROSITE PS00658 http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00658 PROSITE PS50039 http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS50039 PSORT swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/kpsort/swissprot:FOXP2_HUMAN PSORT-B swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/kpsortb/swissprot:FOXP2_HUMAN PSORT2 swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/kpsort2/swissprot:FOXP2_HUMAN Pfam PF00250 http://pfam.xfam.org/family/PF00250 Pfam PF16159 http://pfam.xfam.org/family/PF16159 PharmGKB PA28242 http://www.pharmgkb.org/do/serve?objId=PA28242&objCls=Gene Phobius swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/kphobius/swissprot:FOXP2_HUMAN PhylomeDB O15409 http://phylomedb.org/?seqid=O15409 ProteinModelPortal O15409 http://www.proteinmodelportal.org/query/uniprot/O15409 PubMed 11586359 http://www.ncbi.nlm.nih.gov/pubmed/11586359 PubMed 12189486 http://www.ncbi.nlm.nih.gov/pubmed/12189486 PubMed 12192408 http://www.ncbi.nlm.nih.gov/pubmed/12192408 PubMed 12690205 http://www.ncbi.nlm.nih.gov/pubmed/12690205 PubMed 12853948 http://www.ncbi.nlm.nih.gov/pubmed/12853948 PubMed 14702039 http://www.ncbi.nlm.nih.gov/pubmed/14702039 PubMed 15056695 http://www.ncbi.nlm.nih.gov/pubmed/15056695 PubMed 15489334 http://www.ncbi.nlm.nih.gov/pubmed/15489334 PubMed 26647308 http://www.ncbi.nlm.nih.gov/pubmed/26647308 PubMed 9225980 http://www.ncbi.nlm.nih.gov/pubmed/9225980 RefSeq NP_001166237 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_001166237 RefSeq NP_001166238 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_001166238 RefSeq NP_055306 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_055306 RefSeq NP_683696 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_683696 RefSeq NP_683697 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_683697 RefSeq NP_683698 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_683698 RefSeq XP_016868290 http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=XP_016868290 SMART SM00339 http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00339 SMR O15409 http://swissmodel.expasy.org/repository/smr.php?sptr_ac=O15409 STRING 9606.ENSP00000386200 http://string-db.org/newstring_cgi/show_network_section.pl?identifier=9606.ENSP00000386200&targetmode=cogs SUPFAM SSF46785 http://supfam.org/SUPERFAMILY/cgi-bin/scop.cgi?ipid=SSF46785 UCSC uc003vgx http://genome.ucsc.edu/cgi-bin/hgGene?hgg_gene=uc003vgx&org=rat UniGene Hs.282787 http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=At&CID=Hs.282787 UniProtKB FOXP2_HUMAN http://www.uniprot.org/uniprot/FOXP2_HUMAN UniProtKB-AC O15409 http://www.uniprot.org/uniprot/O15409 charge swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/charge/swissprot:FOXP2_HUMAN eggNOG COG5025 http://eggnogapi.embl.de/nog_data/html/tree/COG5025 eggNOG KOG4385 http://eggnogapi.embl.de/nog_data/html/tree/KOG4385 epestfind swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/epestfind/swissprot:FOXP2_HUMAN garnier swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/garnier/swissprot:FOXP2_HUMAN helixturnhelix swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/helixturnhelix/swissprot:FOXP2_HUMAN hmoment swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/hmoment/swissprot:FOXP2_HUMAN iep swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/iep/swissprot:FOXP2_HUMAN inforesidue swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/inforesidue/swissprot:FOXP2_HUMAN neXtProt NX_O15409 http://www.nextprot.org/db/entry/NX_O15409 octanol swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/octanol/swissprot:FOXP2_HUMAN pepcoil swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepcoil/swissprot:FOXP2_HUMAN pepdigest swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepdigest/swissprot:FOXP2_HUMAN pepinfo swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepinfo/swissprot:FOXP2_HUMAN pepnet swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepnet/swissprot:FOXP2_HUMAN pepstats swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepstats/swissprot:FOXP2_HUMAN pepwheel swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepwheel/swissprot:FOXP2_HUMAN pepwindow swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/pepwindow/swissprot:FOXP2_HUMAN sigcleave swissprot:FOXP2_HUMAN http://rest.g-language.org/emboss/sigcleave/swissprot:FOXP2_HUMAN