DataBaseIDURL or Descriptions
# DOMAINFOXP2_MACMUThe leucine-zipper is required for dimerization and transcriptional repression. {ECO 0000250}.
# EnsemblENSMMUT00000054563ENSMMUP00000044141; ENSMMUG00000008005
# ExpressionAtlasQ8MJ97differential
# FUNCTIONFOXP2_MACMUTranscriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). {ECO 0000250}.
# GO_componentGO:0005634nucleus; IBA:GO_Central.
# GO_functionGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding; IBA:GO_Central.
# GO_functionGO:0003677DNA binding; ISS:UniProtKB.
# GO_functionGO:0042803protein homodimerization activity; ISS:UniProtKB.
# GO_functionGO:0043565sequence-specific DNA binding; IEA:InterPro.
# GO_functionGO:0046872metal ion binding; IEA:UniProtKB-KW.
# GO_processGO:0006351transcription, DNA-templated; IEA:UniProtKB-KW.
# GO_processGO:0021757caudate nucleus development; ISS:UniProtKB.
# GO_processGO:0021758putamen development; ISS:UniProtKB.
# GOslim_componentGO:0005634nucleus
# GOslim_functionGO:0001071nucleic acid binding transcription factor activity
# GOslim_functionGO:0003674molecular_function
# GOslim_functionGO:0003677DNA binding
# GOslim_functionGO:0043167ion binding
# GOslim_processGO:0009058biosynthetic process
# GOslim_processGO:0034641cellular nitrogen compound metabolic process
# GOslim_processGO:0048856anatomical structure development
# Gene3D1.10.10.10-; 1.
# InterProIPR001766Fork_head_dom
# InterProIPR011991WHTH_DNA-bd_dom
# InterProIPR030456TF_fork_head_CS_2
# InterProIPR032354FOXP-CC
# KEGG_Briteko03000Transcription factors
# OrganismFOXP2_MACMUMacaca mulatta (Rhesus macaque)
# PRINTSPR00053FORKHEAD
# PROSITEPS00028ZINC_FINGER_C2H2_1
# PROSITEPS00658FORK_HEAD_2
# PROSITEPS50039FORK_HEAD_3
# PfamPF00250Forkhead
# PfamPF16159FOXP-CC
# ProteomesUP000006718Chromosome 3
# RecNameFOXP2_MACMUForkhead box protein P2
# RefSeqNP_001028193NM_001033021.1
# RefSeqXP_014990203XM_015134717.1
# SIMILARITYContains 1 C2H2-type zinc finger. {ECO0000305}.
# SIMILARITYContains 1 fork-head DNA-binding domain. {ECO:0000255|PROSITE-ProRulePRU00089}.
# SMARTSM00339FH
# SUBCELLULAR LOCATIONFOXP2_MACMUNucleus {ECO 0000305}.
# SUBUNITFOXP2_MACMUForms homodimers and heterodimers with FOXP1 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1. Interacts with FOXP1 (By similarity). {ECO 0000250|UniProtKB O15409, ECO 0000250|UniProtKB P58463}.
# SUPFAMSSF46785SSF46785
# eggNOGCOG5025LUCA
# eggNOGKOG4385Eukaryota
BLASTswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/kblast/swissprot:FOXP2_MACMU
DOI10.1038/nature01025http://dx.doi.org/10.1038/nature01025
EMBLAF512950http://www.ebi.ac.uk/ena/data/view/AF512950
EnsemblENSMMUT00000054563http://www.ensembl.org/id/ENSMMUT00000054563
G-LinksFOXP2_MACMUhttp://link.g-language.org/FOXP2_MACMU/format=tsv
GO_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GO_functionGO:0000981http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000981
GO_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GO_functionGO:0042803http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042803
GO_functionGO:0043565http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043565
GO_functionGO:0046872http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046872
GO_processGO:0006351http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006351
GO_processGO:0021757http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021757
GO_processGO:0021758http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021758
GOslim_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GOslim_functionGO:0001071http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001071
GOslim_functionGO:0003674http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003674
GOslim_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GOslim_functionGO:0043167http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043167
GOslim_processGO:0009058http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009058
GOslim_processGO:0034641http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034641
GOslim_processGO:0048856http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048856
Gene3D1.10.10.10http://www.cathdb.info/version/latest/superfamily/1.10.10.10
GeneID613237http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=613237
GeneTreeENSGT00800000124014http://asia.ensembl.org/Multi/GeneTree/Image?gt=ENSGT00800000124014
HOGENOMHOG000092089http://pbil.univ-lyon1.fr/cgi-bin/view-tree.pl?query=HOG000092089&db=HOGENOM6
HOVERGENHBG051657http://pbil.univ-lyon1.fr/cgi-bin/acnuc-ac2tree?query=HBG051657&db=HOVERGEN
InParanoidQ8MJ97http://inparanoid.sbc.su.se/cgi-bin/gene_search.cgi?id=Q8MJ97
InterProIPR001766http://www.ebi.ac.uk/interpro/entry/IPR001766
InterProIPR011991http://www.ebi.ac.uk/interpro/entry/IPR011991
InterProIPR030456http://www.ebi.ac.uk/interpro/entry/IPR030456
InterProIPR032354http://www.ebi.ac.uk/interpro/entry/IPR032354
KEGG_Briteko03000http://www.genome.jp/dbget-bin/www_bget?ko03000
KEGG_Genemcc:613237http://www.genome.jp/dbget-bin/www_bget?mcc:613237
KEGG_OrthologyKO:K09409http://www.genome.jp/dbget-bin/www_bget?KO:K09409
PRINTSPR00053http://umber.sbs.man.ac.uk/cgi-bin/dbbrowser/sprint/searchprintss.cgi?display_opts=Prints&category=None&queryform=false&prints_accn=PR00053
PROSITEPS00028http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00028
PROSITEPS00658http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00658
PROSITEPS50039http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS50039
PSORT-Bswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/kpsortb/swissprot:FOXP2_MACMU
PSORT2swissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/kpsort2/swissprot:FOXP2_MACMU
PSORTswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/kpsort/swissprot:FOXP2_MACMU
PfamPF00250http://pfam.xfam.org/family/PF00250
PfamPF16159http://pfam.xfam.org/family/PF16159
Phobiusswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/kphobius/swissprot:FOXP2_MACMU
ProteinModelPortalQ8MJ97http://www.proteinmodelportal.org/query/uniprot/Q8MJ97
PubMed12192408http://www.ncbi.nlm.nih.gov/pubmed/12192408
RefSeqNP_001028193http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_001028193
RefSeqXP_014990203http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=XP_014990203
SMARTSM00339http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00339
STRING9544.ENSMMUP00000010501http://string-db.org/newstring_cgi/show_network_section.pl?identifier=9544.ENSMMUP00000010501&targetmode=cogs
SUPFAMSSF46785http://supfam.org/SUPERFAMILY/cgi-bin/scop.cgi?ipid=SSF46785
UniGeneMmu.4784http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=At&CID=Mmu.4784
UniProtKB-ACQ8MJ97http://www.uniprot.org/uniprot/Q8MJ97
UniProtKBFOXP2_MACMUhttp://www.uniprot.org/uniprot/FOXP2_MACMU
chargeswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/charge/swissprot:FOXP2_MACMU
eggNOGCOG5025http://eggnogapi.embl.de/nog_data/html/tree/COG5025
eggNOGKOG4385http://eggnogapi.embl.de/nog_data/html/tree/KOG4385
epestfindswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/epestfind/swissprot:FOXP2_MACMU
garnierswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/garnier/swissprot:FOXP2_MACMU
helixturnhelixswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/helixturnhelix/swissprot:FOXP2_MACMU
hmomentswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/hmoment/swissprot:FOXP2_MACMU
iepswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/iep/swissprot:FOXP2_MACMU
inforesidueswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/inforesidue/swissprot:FOXP2_MACMU
octanolswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/octanol/swissprot:FOXP2_MACMU
pepcoilswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepcoil/swissprot:FOXP2_MACMU
pepdigestswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepdigest/swissprot:FOXP2_MACMU
pepinfoswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepinfo/swissprot:FOXP2_MACMU
pepnetswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepnet/swissprot:FOXP2_MACMU
pepstatsswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepstats/swissprot:FOXP2_MACMU
pepwheelswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepwheel/swissprot:FOXP2_MACMU
pepwindowswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/pepwindow/swissprot:FOXP2_MACMU
sigcleaveswissprot:FOXP2_MACMUhttp://rest.g-language.org/emboss/sigcleave/swissprot:FOXP2_MACMU