DataBaseIDURL or Descriptions
# DOMAINFOXP2_PANTRThe leucine-zipper is required for dimerization and transcriptional repression. {ECO 0000250}.
# EnsemblENSPTRT00000036314ENSPTRP00000033573; ENSPTRG00000019608
# FUNCTIONFOXP2_PANTRTranscriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). {ECO 0000250}.
# GO_componentGO:0005634nucleus; IBA:GO_Central.
# GO_functionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
# GO_functionGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding; IBA:GO_Central.
# GO_functionGO:0001078transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; IEA:Ensembl.
# GO_functionGO:0003677DNA binding; ISS:UniProtKB.
# GO_functionGO:0042803protein homodimerization activity; ISS:UniProtKB.
# GO_functionGO:0046872metal ion binding; IEA:UniProtKB-KW.
# GO_processGO:0002053positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
# GO_processGO:0006351transcription, DNA-templated; IEA:UniProtKB-KW.
# GO_processGO:0007519skeletal muscle tissue development; IEA:Ensembl.
# GO_processGO:0009791post-embryonic development; IEA:Ensembl.
# GO_processGO:0021549cerebellum development; IEA:Ensembl.
# GO_processGO:0021757caudate nucleus development; ISS:UniProtKB.
# GO_processGO:0021758putamen development; ISS:UniProtKB.
# GO_processGO:0021987cerebral cortex development; IEA:Ensembl.
# GO_processGO:0040007growth; IEA:Ensembl.
# GO_processGO:0042297vocal learning; IEA:Ensembl.
# GO_processGO:0043010camera-type eye development; IEA:Ensembl.
# GO_processGO:0048286lung alveolus development; IEA:Ensembl.
# GO_processGO:0048745smooth muscle tissue development; IEA:Ensembl.
# GO_processGO:0060013righting reflex; IEA:Ensembl.
# GO_processGO:0060501positive regulation of epithelial cell proliferation involved in lung morphogenesis; IEA:Ensembl.
# GOslim_componentGO:0005634nucleus
# GOslim_functionGO:0001071nucleic acid binding transcription factor activity
# GOslim_functionGO:0003674molecular_function
# GOslim_functionGO:0003677DNA binding
# GOslim_functionGO:0043167ion binding
# GOslim_processGO:0008150biological_process
# GOslim_processGO:0009058biosynthetic process
# GOslim_processGO:0034641cellular nitrogen compound metabolic process
# GOslim_processGO:0040007growth
# GOslim_processGO:0048856anatomical structure development
# GOslim_processGO:0050877neurological system process
# Gene3D1.10.10.10-; 1.
# InterProIPR001766Fork_head_dom
# InterProIPR011991WHTH_DNA-bd_dom
# InterProIPR030456TF_fork_head_CS_2
# InterProIPR032354FOXP-CC
# KEGG_Briteko03000Transcription factors
# OrganismFOXP2_PANTRPan troglodytes (Chimpanzee)
# PRINTSPR00053FORKHEAD
# PROSITEPS00028ZINC_FINGER_C2H2_1
# PROSITEPS00658FORK_HEAD_2
# PROSITEPS50039FORK_HEAD_3
# PfamPF00250Forkhead
# PfamPF16159FOXP-CC
# ProteomesUP000002277Chromosome 7
# RecNameFOXP2_PANTRForkhead box protein P2
# RefSeqNP_001009020NM_001009020.3
# SIMILARITYContains 1 C2H2-type zinc finger. {ECO0000305}.
# SIMILARITYContains 1 fork-head DNA-binding domain. {ECO:0000255|PROSITE-ProRulePRU00089}.
# SMARTSM00339FH
# SUBCELLULAR LOCATIONFOXP2_PANTRNucleus {ECO 0000305}.
# SUBUNITFOXP2_PANTRForms homodimers and heterodimers with FOXP1 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1. Interacts with FOXP1 (By similarity). {ECO 0000250|UniProtKB O15409, ECO 0000250|UniProtKB P58463}.
# SUPFAMSSF46785SSF46785
# eggNOGCOG5025LUCA
# eggNOGKOG4385Eukaryota
BLASTswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/kblast/swissprot:FOXP2_PANTR
DOI10.1038/nature01025http://dx.doi.org/10.1038/nature01025
EMBLAF512947http://www.ebi.ac.uk/ena/data/view/AF512947
EMBLAF515051http://www.ebi.ac.uk/ena/data/view/AF515051
EMBLAF515052http://www.ebi.ac.uk/ena/data/view/AF515052
EMBLAY064549http://www.ebi.ac.uk/ena/data/view/AY064549
EMBLAY064551http://www.ebi.ac.uk/ena/data/view/AY064551
EMBLAY064552http://www.ebi.ac.uk/ena/data/view/AY064552
EMBLAY064553http://www.ebi.ac.uk/ena/data/view/AY064553
EMBLAY064554http://www.ebi.ac.uk/ena/data/view/AY064554
EMBLAY064555http://www.ebi.ac.uk/ena/data/view/AY064555
EMBLAY064556http://www.ebi.ac.uk/ena/data/view/AY064556
EMBLAY064557http://www.ebi.ac.uk/ena/data/view/AY064557
EMBLAY064558http://www.ebi.ac.uk/ena/data/view/AY064558
EMBLAY064559http://www.ebi.ac.uk/ena/data/view/AY064559
EMBLAY064560http://www.ebi.ac.uk/ena/data/view/AY064560
EMBLAY064561http://www.ebi.ac.uk/ena/data/view/AY064561
EMBLAY064562http://www.ebi.ac.uk/ena/data/view/AY064562
EMBLAY064563http://www.ebi.ac.uk/ena/data/view/AY064563
EMBLAY064564http://www.ebi.ac.uk/ena/data/view/AY064564
EMBLAY064565http://www.ebi.ac.uk/ena/data/view/AY064565
EMBLAY143178http://www.ebi.ac.uk/ena/data/view/AY143178
EnsemblENSPTRT00000036314http://www.ensembl.org/id/ENSPTRT00000036314
G-LinksFOXP2_PANTRhttp://link.g-language.org/FOXP2_PANTR/format=tsv
GO_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GO_functionGO:0000978http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000978
GO_functionGO:0000981http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0000981
GO_functionGO:0001078http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001078
GO_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GO_functionGO:0042803http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042803
GO_functionGO:0046872http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046872
GO_processGO:0002053http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0002053
GO_processGO:0006351http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006351
GO_processGO:0007519http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0007519
GO_processGO:0009791http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009791
GO_processGO:0021549http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021549
GO_processGO:0021757http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021757
GO_processGO:0021758http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021758
GO_processGO:0021987http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021987
GO_processGO:0040007http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0040007
GO_processGO:0042297http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042297
GO_processGO:0043010http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043010
GO_processGO:0048286http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048286
GO_processGO:0048745http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048745
GO_processGO:0060013http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060013
GO_processGO:0060501http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0060501
GOslim_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GOslim_functionGO:0001071http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001071
GOslim_functionGO:0003674http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003674
GOslim_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GOslim_functionGO:0043167http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043167
GOslim_processGO:0008150http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0008150
GOslim_processGO:0009058http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009058
GOslim_processGO:0034641http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034641
GOslim_processGO:0040007http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0040007
GOslim_processGO:0048856http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048856
GOslim_processGO:0050877http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0050877
Gene3D1.10.10.10http://www.cathdb.info/version/latest/superfamily/1.10.10.10
GeneID449627http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=449627
GeneTreeENSGT00800000124014http://asia.ensembl.org/Multi/GeneTree/Image?gt=ENSGT00800000124014
HOGENOMHOG000092089http://pbil.univ-lyon1.fr/cgi-bin/view-tree.pl?query=HOG000092089&db=HOGENOM6
HOVERGENHBG051657http://pbil.univ-lyon1.fr/cgi-bin/acnuc-ac2tree?query=HBG051657&db=HOVERGEN
InParanoidQ8MJA0http://inparanoid.sbc.su.se/cgi-bin/gene_search.cgi?id=Q8MJA0
InterProIPR001766http://www.ebi.ac.uk/interpro/entry/IPR001766
InterProIPR011991http://www.ebi.ac.uk/interpro/entry/IPR011991
InterProIPR030456http://www.ebi.ac.uk/interpro/entry/IPR030456
InterProIPR032354http://www.ebi.ac.uk/interpro/entry/IPR032354
KEGG_Briteko03000http://www.genome.jp/dbget-bin/www_bget?ko03000
KEGG_Geneptr:449627http://www.genome.jp/dbget-bin/www_bget?ptr:449627
KEGG_OrthologyKO:K09409http://www.genome.jp/dbget-bin/www_bget?KO:K09409
OMAPETKLCVhttp://omabrowser.org/cgi-bin/gateway.pl?f=DisplayGroup&p1=PETKLCV
OrthoDBEOG091G08HYhttp://cegg.unige.ch/orthodb/results?searchtext=EOG091G08HY
PRINTSPR00053http://umber.sbs.man.ac.uk/cgi-bin/dbbrowser/sprint/searchprintss.cgi?display_opts=Prints&category=None&queryform=false&prints_accn=PR00053
PROSITEPS00028http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00028
PROSITEPS00658http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00658
PROSITEPS50039http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS50039
PSORT-Bswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/kpsortb/swissprot:FOXP2_PANTR
PSORT2swissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/kpsort2/swissprot:FOXP2_PANTR
PSORTswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/kpsort/swissprot:FOXP2_PANTR
PfamPF00250http://pfam.xfam.org/family/PF00250
PfamPF16159http://pfam.xfam.org/family/PF16159
Phobiusswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/kphobius/swissprot:FOXP2_PANTR
ProteinModelPortalQ8MJA0http://www.proteinmodelportal.org/query/uniprot/Q8MJA0
PubMed12192408http://www.ncbi.nlm.nih.gov/pubmed/12192408
PubMed12524352http://www.ncbi.nlm.nih.gov/pubmed/12524352
RefSeqNP_001009020http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=protein&id=NP_001009020
SMARTSM00339http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00339
SMRQ8MJA0http://swissmodel.expasy.org/repository/smr.php?sptr_ac=Q8MJA0
STRING9598.ENSPTRP00000033573http://string-db.org/newstring_cgi/show_network_section.pl?identifier=9598.ENSPTRP00000033573&targetmode=cogs
SUPFAMSSF46785http://supfam.org/SUPERFAMILY/cgi-bin/scop.cgi?ipid=SSF46785
UniGenePtr.6303http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=At&CID=Ptr.6303
UniProtKB-ACQ8MJA0http://www.uniprot.org/uniprot/Q8MJA0
UniProtKBFOXP2_PANTRhttp://www.uniprot.org/uniprot/FOXP2_PANTR
chargeswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/charge/swissprot:FOXP2_PANTR
eggNOGCOG5025http://eggnogapi.embl.de/nog_data/html/tree/COG5025
eggNOGKOG4385http://eggnogapi.embl.de/nog_data/html/tree/KOG4385
epestfindswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/epestfind/swissprot:FOXP2_PANTR
garnierswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/garnier/swissprot:FOXP2_PANTR
helixturnhelixswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/helixturnhelix/swissprot:FOXP2_PANTR
hmomentswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/hmoment/swissprot:FOXP2_PANTR
iepswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/iep/swissprot:FOXP2_PANTR
inforesidueswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/inforesidue/swissprot:FOXP2_PANTR
octanolswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/octanol/swissprot:FOXP2_PANTR
pepcoilswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepcoil/swissprot:FOXP2_PANTR
pepdigestswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepdigest/swissprot:FOXP2_PANTR
pepinfoswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepinfo/swissprot:FOXP2_PANTR
pepnetswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepnet/swissprot:FOXP2_PANTR
pepstatsswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepstats/swissprot:FOXP2_PANTR
pepwheelswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepwheel/swissprot:FOXP2_PANTR
pepwindowswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/pepwindow/swissprot:FOXP2_PANTR
sigcleaveswissprot:FOXP2_PANTRhttp://rest.g-language.org/emboss/sigcleave/swissprot:FOXP2_PANTR