DataBaseIDURL or Descriptions
# DOMAINFOXP2_PONPYThe leucine-zipper is required for dimerization and transcriptional repression. {ECO 0000250}.
# FUNCTIONFOXP2_PONPYTranscriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). {ECO 0000250}.
# GO_componentGO:0005634nucleus; IEA:UniProtKB-SubCell.
# GO_functionGO:0003677DNA binding; ISS:UniProtKB.
# GO_functionGO:0003700transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
# GO_functionGO:0042803protein homodimerization activity; ISS:UniProtKB.
# GO_functionGO:0043565sequence-specific DNA binding; IEA:InterPro.
# GO_functionGO:0046872metal ion binding; IEA:UniProtKB-KW.
# GO_processGO:0006351transcription, DNA-templated; IEA:UniProtKB-KW.
# GO_processGO:0021757caudate nucleus development; ISS:UniProtKB.
# GO_processGO:0021758putamen development; ISS:UniProtKB.
# GOslim_componentGO:0005634nucleus
# GOslim_functionGO:0001071nucleic acid binding transcription factor activity
# GOslim_functionGO:0003674molecular_function
# GOslim_functionGO:0003677DNA binding
# GOslim_functionGO:0043167ion binding
# GOslim_processGO:0009058biosynthetic process
# GOslim_processGO:0034641cellular nitrogen compound metabolic process
# GOslim_processGO:0048856anatomical structure development
# Gene3D1.10.10.10-; 1.
# InterProIPR001766Fork_head_dom
# InterProIPR011991WHTH_DNA-bd_dom
# InterProIPR030456TF_fork_head_CS_2
# InterProIPR032354FOXP-CC
# OrganismFOXP2_PONPYPongo pygmaeus (Bornean orangutan)
# PRINTSPR00053FORKHEAD
# PROSITEPS00028ZINC_FINGER_C2H2_1
# PROSITEPS00658FORK_HEAD_2
# PROSITEPS50039FORK_HEAD_3
# PfamPF00250Forkhead
# PfamPF16159FOXP-CC
# RecNameFOXP2_PONPYForkhead box protein P2
# SIMILARITYContains 1 C2H2-type zinc finger. {ECO0000305}.
# SIMILARITYContains 1 fork-head DNA-binding domain. {ECO:0000255|PROSITE-ProRulePRU00089}.
# SMARTSM00339FH
# SUBCELLULAR LOCATIONFOXP2_PONPYNucleus {ECO 0000305}.
# SUBUNITFOXP2_PONPYForms homodimers and heterodimers with FOXP1 and FOXP4. Dimerization is required for DNA-binding. Interacts with CTBP1. Interacts with FOXP1 (By similarity). {ECO 0000250|UniProtKB O15409, ECO 0000250|UniProtKB P58463}.
# SUPFAMSSF46785SSF46785
BLASTswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/kblast/swissprot:FOXP2_PONPY
DOI10.1038/nature01025http://dx.doi.org/10.1038/nature01025
EMBLAF512949http://www.ebi.ac.uk/ena/data/view/AF512949
EMBLAF515053http://www.ebi.ac.uk/ena/data/view/AF515053
EMBLAY064600http://www.ebi.ac.uk/ena/data/view/AY064600
EMBLAY064601http://www.ebi.ac.uk/ena/data/view/AY064601
EMBLAY064602http://www.ebi.ac.uk/ena/data/view/AY064602
EMBLAY064603http://www.ebi.ac.uk/ena/data/view/AY064603
EMBLAY064604http://www.ebi.ac.uk/ena/data/view/AY064604
EMBLAY064605http://www.ebi.ac.uk/ena/data/view/AY064605
EMBLAY064606http://www.ebi.ac.uk/ena/data/view/AY064606
EMBLAY064607http://www.ebi.ac.uk/ena/data/view/AY064607
EMBLAY064608http://www.ebi.ac.uk/ena/data/view/AY064608
EMBLAY064609http://www.ebi.ac.uk/ena/data/view/AY064609
EMBLAY064610http://www.ebi.ac.uk/ena/data/view/AY064610
EMBLAY064611http://www.ebi.ac.uk/ena/data/view/AY064611
EMBLAY064612http://www.ebi.ac.uk/ena/data/view/AY064612
EMBLAY064613http://www.ebi.ac.uk/ena/data/view/AY064613
EMBLAY064614http://www.ebi.ac.uk/ena/data/view/AY064614
EMBLAY143181http://www.ebi.ac.uk/ena/data/view/AY143181
EMBLDQ789573http://www.ebi.ac.uk/ena/data/view/DQ789573
G-LinksFOXP2_PONPYhttp://link.g-language.org/FOXP2_PONPY/format=tsv
GO_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GO_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GO_functionGO:0003700http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003700
GO_functionGO:0042803http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0042803
GO_functionGO:0043565http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043565
GO_functionGO:0046872http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0046872
GO_processGO:0006351http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0006351
GO_processGO:0021757http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021757
GO_processGO:0021758http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0021758
GOslim_componentGO:0005634http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0005634
GOslim_functionGO:0001071http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0001071
GOslim_functionGO:0003674http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003674
GOslim_functionGO:0003677http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0003677
GOslim_functionGO:0043167http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0043167
GOslim_processGO:0009058http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0009058
GOslim_processGO:0034641http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0034641
GOslim_processGO:0048856http://amigo.geneontology.org/cgi-bin/amigo/term_details?term=GO:0048856
Gene3D1.10.10.10http://www.cathdb.info/version/latest/superfamily/1.10.10.10
HOGENOMHOG000092089http://pbil.univ-lyon1.fr/cgi-bin/view-tree.pl?query=HOG000092089&db=HOGENOM6
HOVERGENHBG051657http://pbil.univ-lyon1.fr/cgi-bin/acnuc-ac2tree?query=HBG051657&db=HOVERGEN
InterProIPR001766http://www.ebi.ac.uk/interpro/entry/IPR001766
InterProIPR011991http://www.ebi.ac.uk/interpro/entry/IPR011991
InterProIPR030456http://www.ebi.ac.uk/interpro/entry/IPR030456
InterProIPR032354http://www.ebi.ac.uk/interpro/entry/IPR032354
PRINTSPR00053http://umber.sbs.man.ac.uk/cgi-bin/dbbrowser/sprint/searchprintss.cgi?display_opts=Prints&category=None&queryform=false&prints_accn=PR00053
PROSITEPS00028http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00028
PROSITEPS00658http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS00658
PROSITEPS50039http://prosite.expasy.org/cgi-bin/prosite/nicedoc.pl?PS50039
PSORT-Bswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/kpsortb/swissprot:FOXP2_PONPY
PSORT2swissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/kpsort2/swissprot:FOXP2_PONPY
PSORTswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/kpsort/swissprot:FOXP2_PONPY
PfamPF00250http://pfam.xfam.org/family/PF00250
PfamPF16159http://pfam.xfam.org/family/PF16159
Phobiusswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/kphobius/swissprot:FOXP2_PONPY
ProteinModelPortalQ8MJ98http://www.proteinmodelportal.org/query/uniprot/Q8MJ98
PubMed12192408http://www.ncbi.nlm.nih.gov/pubmed/12192408
PubMed12524352http://www.ncbi.nlm.nih.gov/pubmed/12524352
SMARTSM00339http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00339
SUPFAMSSF46785http://supfam.org/SUPERFAMILY/cgi-bin/scop.cgi?ipid=SSF46785
UniProtKB-ACQ8MJ98http://www.uniprot.org/uniprot/Q8MJ98
UniProtKBFOXP2_PONPYhttp://www.uniprot.org/uniprot/FOXP2_PONPY
chargeswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/charge/swissprot:FOXP2_PONPY
epestfindswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/epestfind/swissprot:FOXP2_PONPY
garnierswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/garnier/swissprot:FOXP2_PONPY
helixturnhelixswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/helixturnhelix/swissprot:FOXP2_PONPY
hmomentswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/hmoment/swissprot:FOXP2_PONPY
iepswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/iep/swissprot:FOXP2_PONPY
inforesidueswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/inforesidue/swissprot:FOXP2_PONPY
octanolswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/octanol/swissprot:FOXP2_PONPY
pepcoilswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepcoil/swissprot:FOXP2_PONPY
pepdigestswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepdigest/swissprot:FOXP2_PONPY
pepinfoswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepinfo/swissprot:FOXP2_PONPY
pepnetswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepnet/swissprot:FOXP2_PONPY
pepstatsswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepstats/swissprot:FOXP2_PONPY
pepwheelswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepwheel/swissprot:FOXP2_PONPY
pepwindowswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/pepwindow/swissprot:FOXP2_PONPY
sigcleaveswissprot:FOXP2_PONPYhttp://rest.g-language.org/emboss/sigcleave/swissprot:FOXP2_PONPY